Therapeutic applications of exosomes from adipose-derived stem cells in antifibrosis

被引：0

作者：

Liquan Wang ^{[1
]}

Zhujun Li ^{[1
]}

Yunzhu Li ^{[1
]}

Jiuzuo Huang ^{[1
]}

Nanze Yu ^{[1
]}

Xiao Long ^{[1
]}

机构：

[1] Department of Plastic and Reconstructive Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences

来源：

ChineseJournalofPlasticandReconstructiveSurgery | 2021年 / 3卷 / 03期

基金：

中国国家自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R45 [治疗学];

学科分类号：

100215 ;

摘要：

Fibrosis is a condition in which connective tissue replaces normal parenchymal tissue, resulting in significant tissue remodeling. Fibrosis can affect several organs and pose a serious threat to human health and life. Adiposederived stem cells(ASCs) have been suggested as promising candidates for antifibrotic therapies. Paracrine secretion is one of the key processes in stem cell therapy due to its critical function in cellular communication.ASC-derived exosomes(ASC-exos) are used as tools for restoring and regenerating damaged tissue, and they are now thought to orchestrate antifibrosis-related events. In this review, we summarize the recent findings and present an extensive view of the therapeutic applications of ASC-exos in fibrotic diseases.

引用

页码：161 / 166

页数：6

共 27 条

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