Synthesis and Crystal Structure of α, α′, α″-Trimethyl-1, 4, 7-Triazacyclononane-N, N′, N″-Triacetic Acid

被引:0
作者
魏平荣
金天柱
高松
徐光宪
金钟声
机构
[1] Research Centre of Rare Earth Chemistry Peking University Beijing 100871 PRC
[2] Changchun Institute of Applied Chemistry Academia Sinica Changchun 130022 PRC
[3] Research Centre of Rare Earth Chemistry Peking University Beijing 100871 PRC
关键词
polyazamacrocycle; complex of lanthanum; crystal structure;
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摘要
The development of nuclear magnetic resonance (NMR) imaging as a clinical diagnostic modality has promoted the need for a new class of pharmaceuticals. These drugs would be administered to a patient to enhance the image contrast between the normal and diseased tissues. The image intensity in ~1HNMR imaging, composed of the NMR signals of water protons, is dependent on the nuclear relaxation times. Complexes of paramagnetic transition and lanthanide ions, which can decrease the relaxation times of nearby nuclei via dipolar interactions, have received much attention as the potential con-
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页码:467 / 470
页数:4
相关论文
共 3 条
  • [1] Brasch,R. C. Radiology . 1983
  • [2] Lauffer,R.B. Chemical Reviews . 1987
  • [3] Desreux,J. F. Inorganic Chemistry . 1980