Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy

被引：0
作者：
Jian Ya LING
机构：
来源：
Chinese Chemical Letters | 2005年 / 01期
关键词：
Cordycepin; calf thymus DNA; Raman spectroscopy; conformation;
D O I：
暂无
中图分类号：
O657.37 [拉曼光谱分析法];
学科分类号：
070302 ; 081704 ;
摘要：
The interaction of cordycepin with calf thymus DNA was investigated at physiological pH with drug/DNA molar ratio of 8. The Raman spectroscopy results indicated that the intercalation of high concentration cordycepin and the interaction of cordycepin with PO2 group led to a major reduction of B-form DNA structure in favor of A-form DNA.
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页码：71 / 74
页数：4
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