Transient elastography for the assessment of chronic liver disease: Ready for the clinic?

被引:10
|
作者
JFL Cobbold
S Morin
SD Taylor-Robinson
机构
[1] Division of Medicine Faculty of Medicine Imperial College London London United Kingdom
[2] Division of Medicine Faculty of Medicine Imperial College London London United Kingdom
基金
英国医学研究理事会;
关键词
FibroScan; Transient elastography; Liver stiffness measurement; Hepatic fi brosis; Hepatitis;
D O I
暂无
中图分类号
R575 [肝及胆疾病];
学科分类号
1002 ; 100201 ;
摘要
Transient elastography is a recently developed non- invasive technique for the assessment of hepatic fi brosis. The technique has been subject to rigorous evaluation in a number of studies in patients with chronic liver disease of varying aetiology. Transient elastography has been compared with histological assessment of percutaneous liver biopsy, with high sensitivity and specificity for the diagnosis of cirrhosis, and has also been used to assess pre-cirrhotic disease. However, the cut-off values between different histological stages vary substantially in different studies, patient groups and aetiology of liver disease. More recent studies have examined the possible place of transient elastography in clinical practice, including risk stratifi cation for the development of complications of cirrhosis. This review describes the technique of transient elastography and discusses the interpretation of recent studies, emphasizing its applicability in the clinical setting.
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页码:4791 / 4797
页数:7
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