Studies on the biosynthesis of arteannuin Ⅰ.The biosynthesis of arteannuinic acid in Artemisia annua L.

被引:0
|
作者
HUANG Jing-Jian ZHOU Feng-Yi WU Lian-Fen ZHEN Gui-Hui Shanghai Institute of Organic Chemistry
Academia Sinica
Shanghai
机构
关键词
Studies on the biosynthesis of arteannuin; The biosynthesis of arteannuinic acid in Artemisia annua L; acid;
D O I
暂无
中图分类号
学科分类号
摘要
Arteannuin(Qinghaosu)(1)is a very potent natural antimalarial isolated from theChinese medicinal herb,Artemisia annua L.(Qinghao).Its chemical structure elucidation andtotal synthesis have already been achieved.In view of its unusual sesquiterpene structureof an endoperoxide ketal-acetal lactone and its specific biological activity,the authours havebeen studying the problem of the biosynthesis of 1 since 1984.From the consideration of thegeneral isoprene principle in the biogenesis of the sesquiterpene and the finding of all the iso-
引用
收藏
页码:383 / 385
页数:3
相关论文
共 50 条
  • [41] Effect of light irradiation on hairy root growth and artemisinin biosynthesis of Artemisia annua L
    Liu, CZ
    Guo, C
    Wang, YC
    Ouyang, F
    PROCESS BIOCHEMISTRY, 2002, 38 (04) : 581 - 585
  • [42] Studies on the structure and synthesis of arteannuin and its related compounds——Ⅹ.The stereocontrolled synthesis of arteannuin and deoxyarteannuin from arteannuinic acid
    XU Xing-xiang ZHU Jie HUANG Da-zhong ZHOU Wei-shan(CHOU Wei-shan) Shanghai Institute of Organic Chemistry
    ActaChimicaSinica(EnglishEdition), 1983, (01) : 98 - 99
  • [43] Antioxidant capacities of Artemisia annua L. leaves and enzymatically treated Artemisia annua L. in vitro and in broilers
    Wan, X. L.
    Niu, Y.
    Zheng, X. C.
    Huang, Q.
    Su, W. P.
    Zhang, J. F.
    Zhang, L. L.
    Wang, T.
    ANIMAL FEED SCIENCE AND TECHNOLOGY, 2016, 221 : 27 - 34
  • [44] Chromatin Accessibility Is Associated with Artemisinin Biosynthesis Regulation in Artemisia annua
    Zhou, Limeng
    Huang, Yingzhang
    Wang, Qi
    Guo, Dianjing
    MOLECULES, 2021, 26 (04):
  • [45] Promoting Artemisinin Biosynthesis in Artemisia annua Plants by Substrate Channeling
    Han, Junli
    Wang, Hongzhen
    Kanagarajan, Selvaraju
    Hao, Mengshu
    Lundgren, Anneli
    Brodelius, Peter E.
    MOLECULAR PLANT, 2016, 9 (06) : 946 - 948
  • [46] Stimulation of artemisinin biosynthesis in Artemisia annua hairy roots by oligogalacturonides
    Zhang, Ben
    Zou, Ting
    Lu, Yan Hua
    Wang, Jian Wen
    AFRICAN JOURNAL OF BIOTECHNOLOGY, 2010, 9 (23): : 3437 - 3442
  • [47] Strategies to increase the biosynthesis of artemisinin in Artemisia annua and A. afra
    Meyer, J. J. M.
    Kruger, F. J. L.
    Hussein, A.
    Muranaka, T.
    Seki, H.
    SOUTH AFRICAN JOURNAL OF BOTANY, 2011, 77 (02) : 543 - 543
  • [48] The SPB-Box Transcription Factor AaSPL2 Positively Regulates Artemisinin Biosynthesis in Artemisia annua L.
    Lv, Zongyou
    Wang, Yun
    Liu, Yan
    Peng, Bowen
    Zhang, Lei
    Tang, Kexuan
    Chen, Wansheng
    FRONTIERS IN PLANT SCIENCE, 2019, 10
  • [49] Enhancement of artemisinin biosynthesis by overexpressing dxr, cyp71av1 and cpr in the plants of Artemisia annua L.
    Xiang, Lien
    Zeng, Lixia
    Yuan, Yuan
    Chen, Min
    Wang, Fang
    Liu, Xiaoqiang
    Zeng, Lingjiang
    Lan, Xiaozhong
    Liao, Zhihua
    PLANT OMICS, 2012, 5 (06) : 503 - 507
  • [50] RNAi-mediated modulation of squalene synthase gene expression in Artemisia annua L. and its impact on artemisinin biosynthesis
    Athar Ali
    Malik Mobeen Ahmad
    Mather Ali Khan
    Parul Saxena
    Shazia Khan
    Malik Zainul Abdin
    Rendiconti Lincei, 2017, 28 : 731 - 741