Studies on the biosynthesis of arteannuin Ⅰ.The biosynthesis of arteannuinic acid in Artemisia annua L.

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作者：
HUANG Jing-Jian ZHOU Feng-Yi WU Lian-Fen ZHEN Gui-Hui Shanghai Institute of Organic Chemistry
Academia Sinica
Shanghai
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来源：
ActaChimicaSinica(EnglishEdition) | 1988年 / 04期
关键词：
Studies on the biosynthesis of arteannuin; The biosynthesis of arteannuinic acid in Artemisia annua L; acid;
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摘要：
Arteannuin(Qinghaosu)(1)is a very potent natural antimalarial isolated from theChinese medicinal herb,Artemisia annua L.(Qinghao).Its chemical structure elucidation andtotal synthesis have already been achieved.In view of its unusual sesquiterpene structureof an endoperoxide ketal-acetal lactone and its specific biological activity,the authours havebeen studying the problem of the biosynthesis of 1 since 1984.From the consideration of thegeneral isoprene principle in the biogenesis of the sesquiterpene and the finding of all the iso-
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页码：383 / 385
页数：3
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