Microarray analysis of gene expression profiles in the bovine mammary gland during lactation

被引:0
作者
HOU XiaoMingLI QingZhang HUANG TianYing Key Laboratory of Dairy Science of Education MinistryNortheast Agricultural UniversityHarbin China [150030 ]
机构
关键词
mammary gland; microarray; lactation; genomics; gene expression profile;
D O I
暂无
中图分类号
Q78 [基因工程(遗传工程)]; S823 [牛];
学科分类号
071007 ; 0836 ; 090102 ; 0905 ;
摘要
Mammary glands undergo functional and metabolic changes during virgin,lactation and dry periods.A total of 122 genes were identified as differentially expressed,including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods.Gene ontology analysis showed the functional classification of the up-regulated genes in lactation,including transport,biosynthetic process,signal transduction,catalytic activity,immune system process,cell death,and positive regulation of the developmental process.Microarray data clarified molecular events in bovine mammary gland lactation.
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页码:248 / 256
页数:9
相关论文
共 8 条
[1]   Wound repair and proliferation of bronchial epithelial cells regulated by CTNNAL1 [J].
Xiang, Yang ;
Tan, Yu-Rong ;
Zhang, Jian-Song ;
Qin, Xiao-Qun ;
Hu, Bi-Bo ;
Wang, Yue ;
Qu, Fei ;
Liu, Hui-Jun .
JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 103 (03) :920-930
[2]  
Influence of negative energy balance on cyclicity and fertility in the high producing dairy cow[J] . D.C. Wathes,M. Fenwick,Z. Cheng,N. Bourne,S. Llewellyn,D.G. Morris,D. Kenny,J. Murphy,R. Fitzpatrick.Theriogenology . 2007
[3]  
Analysis of Gene Expression in Bovine Testis Tissue Prior to Ectopic Testis Tissue Xenografting and During the Grafting Period1[J] . Jonathan A. Schmidt,Jeanene Mde Avila,Derek J. McLean.Biology of Reproduction . 2007 (6)
[4]   Milk yield and mammary growth effects due to increased milking frequency during early lactation [J].
Hale, SA ;
Capuco, AV ;
Erdman, RA .
JOURNAL OF DAIRY SCIENCE, 2003, 86 (06) :2061-2071
[5]  
Functional Development of the Mammary Gland: Use of Expression Profiling and Trajectory Clustering to Reveal Changes in Gene Expression During Pregnancy, Lactation, and Involution[J] . Michael C. Rudolph,James L. McManaman,Larry Hunter,Tzulip Phang,Margaret C. Neville.Journal of Mammary Gland Biology and Neoplasia . 2003 (3)
[6]   Mammary gland membrane transport systems [J].
Shennan, DB .
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 1998, 3 (03) :247-258
[7]   Structure and expression of the mouse casein gene locus [J].
Rijnkels, M ;
Wheeler, DA ;
deBoer, HA ;
Pieper, FR .
MAMMALIAN GENOME, 1997, 8 (01) :9-15
[8]  
Metabolic adaptations in mammary gland during the declining phase of lactation .2 Wilde CJ,and Knight CH. J Dairy Sci . 1989