Small RNA biology:From fundamental studies to applications

被引：0
作者：
LI ZhengHe [1 ]
ZHOU XuePing [1 ]
机构：
[1] State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University
来源：
Science China(Life Sciences) | 2013年 / 11期
基金：
中国国家自然科学基金;
关键词：
RNA; gene; Small RNA biology; siRNAs;
D O I：
暂无
中图分类号：
Q522 [核糖（醣）核酸（RNA）];
学科分类号：
071010 ; 081704 ;
摘要：
The discovery of RNA silencing as a sequence-specific gene regulation mechanism in eukaryotes has been heralded as the most exciting breakthrough in current biology.The seminal work of Baulcombe and Hamilton in 1999 provided a key insight into the potential function of a tiny RNA species of approximately 25 nucleotides(nt)in RNA silencing in plants[1].Subsequently,Tuschl and colleagues[2,3]demonstrated that small RNAs of similar size mediated
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页码：1059 / 1062
页数：4
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