Objective To investigate the effects of Ang-1 on renal hypoxia.Methods SD diabetic rat model was con-structed by intraperitoneal injection with streptozotocin.Then all the rats were randomly divided into four groups:normal control group (NC group),diabetic group (DM group),Ang-1 treatment group (AV group),and blank vector group (BV group).Eight weeks after the diabetic model was constructed,AV group was treated with Ad-