Advances in drug delivery system for platinum agents based combination therapy

被引：0
作者：
Xiang Kang [1 ]
HaiHua Xiao [2 ,3 ]
HaiQin Song [4 ,5 ]
XiaBin Jing [2 ]
LeSan Yan [2 ,3 ]
RuoGu Qi [2 ,3 ]
机构：
[1] Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
[2] State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
[3] University of Chinese Academy of Sciences
[4] Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
[5] Shanghai Minimally Invasive Surgery Center
来源：
Cancer Biology & Medicine | 2015年 / 12卷 / 04期
关键词：
Cancer; drug delivery; combination therapy; platinum;
D O I：
暂无
中图分类号：
R730.5 [肿瘤治疗学];
学科分类号：
100214 ;
摘要：
Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To conquer these problems, new strategies should be adopted for platinum drug based chemotherapy. Modern nanotechnology has been widely employed in the delivery of various therapeutics and diagnostic. It provides the possibility of targeted delivery of a certain anticancer drug to the tumor site, which could minimize toxicity and optimize the drug efficacy. Here, in this review, we focused on the recent progress in polymer based drug delivery systems for platinum-based combination therapy.
引用
收藏
页码：362 / 374
页数：13
相关论文
共 28 条
[11]  
A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors. Rademaker-Lakhai Jeany M,Terret Catherine,Howell Stephen B,Baud Christiane M,De Boer Richard F,Pluim Dick,Beijnen Jos H,Schellens Jan H M,Droz Jean-Pierre. Clinical cancer research : an official journal of the American Association for Cancer Research . 2004
[12]  
Searching for the magic bullet: anticancer platinum drugs which can be accumulated or activated in the tumor tissue. M Galanski,BK Keppler. Anti-cancer agents in medicinal chemistry . 2007
[13]   A novel probe for the non-invasive detection of tumor-associated inflammation [J].
Balducci, Anthony ;
Wen, Yi ;
Zhang, Yang ;
Helfer, Brooke M. ;
Hitchens, T. Kevin ;
Meng, Wilson S. ;
Wesa, Amy K. ;
Janjic, Jelena M. .
ONCOIMMUNOLOGY, 2013, 2 (02)
[14]   A prodrug strategy to deliver cisplatin(IV) and paclitaxel in nanomicelles to improve efficacy and tolerance [J].
Xiao, Haihua ;
Song, Haiqin ;
Yang, Qiang ;
Cai, Haidong ;
Qi, Ruogu ;
Yan, Lesan ;
Liu, Shi ;
Zheng, Yonghui ;
Huang, Yubin ;
Liu, Tongjun ;
Jing, Xiabin .
BIOMATERIALS, 2012, 33 (27) :6507-6519
[15]  
Nanoparticle Delivery of Cancer Drugs[J] . Andrew Z. Wang,Robert Langer,Omid C. Farokhzad.Annual Review of Medicine . 2012 (1)
[16]  
Understanding resistance to combination chemotherapy[J] . Justin R. Pritchard,Douglas A. Lauffenburger,Michael T. Hemann.Drug Resistance Updates . 2012 (5-6)
[17]  
A Phase II Study of Lipoplatin （Liposomal Cisplatin）/Vinorelbine Combination in HER-2/neu–Negative Metastatic Breast Cancer[J] . Fadi S. Farhat,Sally Temraz,Joseph Kattan,Khaled Ibrahim,Nizar Bitar,Nadine Haddad,Rahif Jalloul,Hassan A. Hatoum,Ghazi Nsouli,Ali I. Shamseddine.Clinical Breast Cancer . 2011 (6)
[18]   Anticancer Platinum (IV) Prodrugs with Novel Modes of Activity [J].
Chin, Chee Fei ;
Wong, Daniel Yuan Qiang ;
Jothibasu, Ramasamy ;
Ang, Wee Han .
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2011, 11 (21) :2602-2612
[19]  
Improved anti‐tumor activity of stabilized anthracycline polymeric micelle formulation, NC‐6300[J] . IulianBobe,HiroyukiSaito,NaoyaShibata,RyosukeTanaka,TatsuyukiHayashi,YasukiKato.Cancer Science . 2010 (1)
[20]   Nanoparticle-assisted combination therapies for effective cancer treatment [J].
Hu, Che-Ming Jack ;
Aryal, Santosh ;
Zhang, Liangfang .
THERAPEUTIC DELIVERY, 2010, 1 (02) :323-334
123