Advances in drug delivery system for platinum agents based combination therapy

被引：0

作者：

Xiang Kang ^{[1
]}

HaiHua Xiao ^{[2
,3
]}

HaiQin Song ^{[4
,5
]}

XiaBin Jing ^{[2
]}

LeSan Yan ^{[2
,3
]}

RuoGu Qi ^{[2
,3
]}

机构：

[1] Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

[2] State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences

[3] University of Chinese Academy of Sciences

[4] Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

[5] Shanghai Minimally Invasive Surgery Center

来源：

Cancer Biology & Medicine | 2015年 / 12卷 / 04期

关键词：

Cancer; drug delivery; combination therapy; platinum;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 ;

摘要：

Platinum-based anticancer agents are widely used as first-line drugs in cancer chemotherapy for various solid tumors. However, great side effects and occurrence of resistance remain as the major drawbacks for almost all the platinum drugs developed. To conquer these problems, new strategies should be adopted for platinum drug based chemotherapy. Modern nanotechnology has been widely employed in the delivery of various therapeutics and diagnostic. It provides the possibility of targeted delivery of a certain anticancer drug to the tumor site, which could minimize toxicity and optimize the drug efficacy. Here, in this review, we focused on the recent progress in polymer based drug delivery systems for platinum-based combination therapy.

引用

页码：362 / 374

页数：13

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