Synthesis and Crystal Structure of 2-Ethoxy-3-n-butyl-benzofuro [2,3-d]pyrimidin-4(3H)-one

被引：0

作者：

胡扬根

丁明武

机构：

[1] Key Laboratory of Pesticide & Chemical Biology of Ministry of Education Central China Normal University

[2] Key Laboratory of Pesticide & Chemical Biology of Ministry of Education Central China Normal University

[3] Wuhan 430079 China Department of Comment Medicinal Chemistry Yunyang Medical College Shiyan 442000 China

来源：

Chinese Journal of Structural Chemistry | 2008年 / 01期

基金：

中国国家自然科学基金;

关键词：

crystal structure; benzo[4; 5]furo[2; 3-d]pyrimidin-4(3H)-one; aza-Wittig reaction; synthesis;

D O I：

10.14102/j.cnki.0254-5861.2008.01.009

中图分类号：

O621.2 [有机化合物性质];

学科分类号：

070303 ; 081704 ;

摘要：

The crystal structure of the new title compound 2-ethoxy-3-n-butyl- benzofuro[2,3-d]pyrimidin-4(3H)-one (C16H18N2O3, Mr = 286.32) has been prepared and determined by single- crystal X-ray diffraction. The crystal is of monoclinic, space group P21/c with a = 13.7167(14), b = 13.113(1), c = 8.378(1) , β = 98.992(2)°, V = 1488.4(3) 3, Z = 4, Dc = 1.278, F(000) = 608, μ = 0.089 mm-1, MoKa radiation (λ = 0.71073), R = 0.0498, wR = 0.1238 for 2336 observed reflections with I > 2σ(I). X-ray diffraction analysis reveals that all ring atoms in the benzo[4, 5]furo [2,3-d] pyrimi- dinone moieties are almost coplanar.

引用

页码：21 / 24

页数：4

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