Synthesis and NO production inhibition of novel Mannich base derivatives of irisolidone

被引:0
|
作者
Jiao Wang~a Ying Zhong~(a
机构
关键词
Irisolidone; Mannich reaction; Mannich base; Nitric oxide(NO)production inhibition;
D O I
暂无
中图分类号
O621.2 [有机化合物性质];
学科分类号
070303 ; 081704 ;
摘要
Five new C-8 Mannich base derivatives of irisolidone 2a-2e were synthesized and their nitric oxide(NO)production inhibitory activity was evaluated.Compounds 2a,2b,2c and 2e displayed stronger activities in vitro than the parent compound irisolidone.
引用
收藏
页码:387 / 389
页数:3
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