Biomarkers for Primary Sjgren's Syndrome

被引：4

作者：

Weiqian Chen ^{[1
,2
]}

Heng Cao ^{[1
]}

Jin Lin ^{[1
]}

Nancy Olsen ^{[2
]}

Song Guo Zheng ^{[2
]}

机构：

[1] Division of Rheumatology, The First Affiliated Hospital, College of Medicine, Zhejiang University

[2] Division of Rheumatology, Penn State University Hershey College of Medicine

来源：

Genomics,Proteomics & Bioinformatics | 2015年 / 13卷 / 04期

关键词：

Biomarker; Fms-like tyrosine kinase 3 ligand; Myxovirus-resistance protein A; Non-coding RNAs; Saliva; Sjo¨gren syndrome;

D O I：

暂无

中图分类号：

R593.2 [自身免疫性疾病、结缔组织疾病];

学科分类号：

1002 ; 100201 ;

摘要：

Primary Sjo¨gren’s syndrome(p SS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of p SS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in p SS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjo¨gren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.

引用

页码：219 / 223

页数：5

共 16 条

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