Synthesis of Novel 1,3-Dioxolane Nucleoside Analogues

被引：0

作者：

蔡冬梅

林昆华

李明宗

温集武

李鸿艳

尤田耙

机构：

[1] DepartmentofChemistry,UniversityofScienceandTechnologyofChina,Hefei,Anhui,China,DepartmentofChemistry,ShanghaiUniversity,Shanghai,China,DepartmentofChemistry,UniversityofScienceandTechnologyofChina,Hefei,Anhui,China,DepartmentofChemistry,UniversityofScienc

来源：

Chinese Journal of Chemistry | 2004年 / 12期

关键词：

nucleoside; 1; 3-dioxolane; tiazofurin; Ribavirin; imidazole;

D O I：

暂无

中图分类号：

O629 [天然化合物];

学科分类号：

070303 ; 081704 ;

摘要：

Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole- 4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan- 4-yl)-4-nitroimidazole and 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4,5-dicyanoimidazole were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, 1H NMR, 13C NMR spectra and elemental analysis.

引用

页码：1425 / 1431+1388 +1388

页数：8

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