Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips

被引:0
|
作者
SHI Xiao Wei
SHI Bo Hui
LYU Ai Li
ZHANG Feng
ZHOU Tian Tian
GUO Xiong
机构
[1] Department of Pediatrics,The First Affiliated Hospital of the Medical College of Xi’an Jiaotong University
[2] Department of Oncosurgery,The First Affiliated Hospital of the Medical College of Xi’an Jiaotong University
[3] School of Public Health,Health Science Center,Xi’an Jiaotong University,Key Laboratory of Environment and Gene Related Diseases of Ministry of Education,Key Laboratory of Trace Elements and Endemic Diseases of Ministry of Health
基金
中国国家自然科学基金;
关键词
KBD; Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips; DNA;
D O I
暂无
中图分类号
R684.1 [大骨节病];
学科分类号
1002 ; 100210 ;
摘要
To understand how differentially methylated genes(DMGs)might affect the pathogenesis of Kashin-Beck disease(KBD).Genome-wide methylation profiling of whole blood from 12matched KBD and controls pairs was performed using a high-resolution Infinium 450 K methylation array.In total,97 CpG sites were differentially
引用
收藏
页码:539 / 543
页数:5
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