ANGIOTENSIN Ⅱ-INDUCED CELLULAR HYPERTROPHY: POTENTIAL ROLE OF THE PROTEOLYTIC ACTIVITY IN CULTURED PROXIMAL TUBULE CELLS (LLC-PK1)

被引:0
作者
Liliana Schaefer
Spiros Vamuakas
Roland M Schaefer
Markus Teschner
August Heidiand
机构
[1] Division of Nephrology. University of Wuerzburg
[2] Germany
关键词
LLC-PK1; POTENTIAL ROLE OF THE PROTEOLYTIC ACTIVITY IN CULTURED PROXIMAL TUBULE CELLS; INDUCED CELLULAR HYPERTROPHY; PK; ANGIOTENSIN;
D O I
暂无
中图分类号
R692 [肾疾病];
学科分类号
1002 ; 100210 ;
摘要
In a number of renal disease tubular epithelial cells often display hypertrophy rather than hyperplasia. This hypertrophy, characterized by an increase in protein conten and cell size, as well as an accumulation of extracellular matrix, is a key process which may lead subsequently to tubulointerstitial fibrosis and end-stage renal failure.
引用
收藏
页码:77 / 77
页数:1
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