Posttreatment Lyme disease syndrome and myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review and comparison of pathogenesis

被引:0
作者
Bai Natalie A. [1 ]
Richardson Christie S. [1 ]
机构
[1] Department of Psychiatry
[2] Rowan-Virtua School of Osteopathic Medicine
[3] Mount Laurel
[4] New Jersey
[5] USA
关键词
chronic fatigue syndrome; Lyme disease; myalgic encephalitis; posttreatment Lyme disease syndrome; systematic review;
D O I
暂无
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Lyme disease is the most common vector-borne illness in the United States and has been causing significant morbidity since its discovery in 1977. It is well-documented that about 10% of patients properly treated with antibiotics never fully recover, but instead go on to develop a chronic illness dubbed, posttreatment Lyme disease syndrome (PTLDS) characterized by severe fatigue, cognitive slowing, chronic pain, and sleep difficulties. This review includes 18 studies that detail the symptoms of patients with PTLDS and uses qualitative analysis to compare them to myalgic encephalitis/chronic fatigue syndrome (ME/CFS), a strikingly similar syndrome. In the majority of the PTLDS studies, at least four of the six major symptoms of ME/CFS were also noted, including substantial impairment in activity level and fatigue for more than 6 months, post-exertional malaise, and unrefreshing sleep. In one of the included PTLDS articles, 26 of the 29 ME/CFS symptoms were noted. This study adds to the expanding literature on the post-active phase of infection syndromes, which suggests that chronic illnesses such as PTLDS and ME/CFS have similar pathogenesis despite different infectious origins.
引用
收藏
相关论文
共 24 条
  • [1] CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells..T Kuwabara;F Ishikawa;T Yasuda;K Aritomi;H Nakano;Y Tanaka;Y Okada;M Lipp;T Kakiuchi;.J Immunol.2009,
  • [2] Kundalini Yoga for Post-Treatment Lyme Disease: A Preliminary Randomized Study
    Murray, Lilly
    Alexander, Charles
    Bennett, Clair
    Kuvaldina, Mara
    Khalsa, Gurucharan
    Fallon, Brian
    [J]. HEALTHCARE, 2022, 10 (07)
  • [3] Management and clinical outcomes of Lyme disease in acute care facilities in 2 endemic regions of Quebec; Canada: a multicentre retrospective cohort study..[J].Musonera Jean B;Valiquette Louis;Baron Geneviève;Milord François;Marcoux Dominique;Thivierge Karine;BedardDallaire Samuel;Pelletier Andrée A;Lachance Raphaël;Bourget Jeremy;Simard Catherine;Cantin Emmanuelle;Abbasi Farhad;Haraoui LouisPatrick;Carignan Alex.CMAJ open.2022, 2
  • [4] Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study..[J].Aucott John N;Yang Ting;Yoon Isaac;Powell Debra;Geller Steven A;Rebman Alison W.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.2022,
  • [5] A multimodal neuroimaging study of brain abnormalities and clinical correlates in post treatment Lyme disease
    Marvel, Cherie L.
    Alm, Kylie H.
    Bhattacharya, Deeya
    Rebman, Alison W.
    Bakker, Arnold
    Morgan, Owen P.
    Creighton, Jason A.
    Kozero, Erica A.
    Venkatesan, Arun
    Nadkarni, Prianca A.
    Aucott, John N.
    [J]. PLOS ONE, 2022, 17 (10):
  • [6] Characterizing Post-treatment Lyme Disease Syndrome: A Mixed Methods Study of Patients at a Lyme Disease Clinic in Rhode Island..[J].Vargas Sara E;Guillen Melissa;Stout Claire D;McCarthy Meghan;Canfield Dylan;Tolliver Eric;Cunnane Sabrina;Flanigan Timothy.Rhode Island medical journal (2013).2021, 8
  • [7] Post-Treatment Lyme Disease Syndrome: Need for Diagnosis and Treatment
    Maksimyan, Simona
    Syed, Munir S.
    Soti, Varun
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (10)
  • [8] Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)-A Systemic Review and Comparison of Clinical Presentation and Symptomatology
    Wong, Timothy L.
    Weitzer, Danielle J.
    [J]. MEDICINA-LITHUANIA, 2021, 57 (05):
  • [9] PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews..[J].Page Matthew J;Moher David;Bossuyt Patrick M;Boutron Isabelle;Hoffmann Tammy C;Mulrow Cynthia D;Shamseer Larissa;Tetzlaff Jennifer M;Akl Elie A;Brennan Sue E;Chou Roger;Glanville Julie;Grimshaw Jeremy M;Hróbjartsson Asbjørn;Lalu Manoj M;Li Tianjing;Loder Elizabeth W;MayoWilson Evan;McDonald Steve;McGuinness Luke A;Stewart Lesley A;Thomas James;Tricco Andrea C;Welch Vivian A;Whiting Penny
  • [10] Symptom heterogeneity and patient subgroup classification among US patients with post-treatment Lyme disease: an observational study
    Rebman, Alison W.
    Yang, Ting
    Aucott, John N.
    [J]. BMJ OPEN, 2021, 11 (01):