Trichosanthin can spontaneously penetrate phospholipid monolayer under acid condition

被引：0
|
作者：
Ricky N.S.Wong
机构：
[1] Biological Department
[2] Hong Kong Baptist University
[3] China
来源：
ChineseScienceBulletin | 1999年 / 20期
关键词：
trichosanthin (TCS); lipid monolayer; critical insertion pressure;
D O I：
暂无
中图分类号：
R284 [中药化学];
学科分类号：
摘要：
Tianhuafen is a kind of traditional Chinese medicine for abortion, which has long been used in China. The basic protein trichosanthin (TCS) is responsible for such activity. As a ribosome inactivating protein (RIP), trichosanthin removes A4304 in the 28s rRNA via the N-glycosidase activity and inactivates the ribosome. However, it remains unclear how TCS can
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页码：1892 / 1895
页数：4
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