Trichosanthin can spontaneously penetrate phospholipid monolayer under acid condition

被引:0
|
作者
Ricky N.S.Wong
机构
[1] Biological Department
[2] Hong Kong Baptist University
[3] China
关键词
trichosanthin (TCS); lipid monolayer; critical insertion pressure;
D O I
暂无
中图分类号
R284 [中药化学];
学科分类号
摘要
Tianhuafen is a kind of traditional Chinese medicine for abortion, which has long been used in China. The basic protein trichosanthin (TCS) is responsible for such activity. As a ribosome inactivating protein (RIP), trichosanthin removes A4304 in the 28s rRNA via the N-glycosidase activity and inactivates the ribosome. However, it remains unclear how TCS can
引用
收藏
页码:1892 / 1895
页数:4
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