Recurrence after endoscopic piecemeal mucosal resection for large sessile colorectal polyps

被引:0
作者
Guh Jung Seo [1 ]
Dae Kyung Sohn [1 ]
Kyung Su Han [1 ]
Chang Won Hong [1 ]
Byung Chang Kim [1 ]
Ji Won Park [1 ]
Hyo Seong Choi [1 ]
Hee Jin Chang [1 ]
Jae Hwan Oh [1 ]
机构
[1] Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center
关键词
Colonoscopy; Colorectal neoplasm; Endoscopic piecemeal mucosal resection; Large sessile polyps;
D O I
暂无
中图分类号
R656.9 [结肠];
学科分类号
1002 ; 100210 ;
摘要
AIM: To evaluate the safety and outcomes of endoscopic piecemeal mucosal resection (EPMR) for large sessile colorectal polyps. METHODS: The patients enrolled in this study were 47 patients with 50 large sessile polyps (diameter, 2 cm or greater) who underwent EPMR using a submucosal saline injection technique between December 2002 and October 2005. All medical records, including characteristics of the patients and polyps, complications, and recurrences, were retrospectively reviewed. The first follow-up endoscopic examination was performed at 3-6 mo after initial endoscopic resection, and the second at 12 mo postEPMR. Subsequent surveillance colonoscopic examinations were individualized, taking risk factors into account. RESULTS: The patients were 23 men and 24 women,with a mean age of 60 years. Mean polyp size was 30.1 mm. Of 50 polyps identified, 34 (68%) were benign and 16 (32%) were malignant. There were 6 (12%) cases with EPMR-related bleeding: 5 intra-procedural and 1 early post-procedural bleeding. All bleeding episodes were managed by endoscopic clipping or argon beam coagulation. There were no perforations. Recurrence was identified in 5 cases (12.2%): 4 local recurrences detected at 3 mo post-EPMR and 1 local recurrence detected at 14 mo post-EPMR. The recurrence rate after EPMR was 3.1% for benign polyps and 33.3% for malignant polyps (P < 0.05). Median follow-up time was 37 mo. CONCLUSION: EPMR is safe, but should be applied carefully in malignant polyps. Close follow-up endoscopic examinations are necessary for early detection of recurrence.
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收藏
页码:2806 / 2811
页数:6
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