The effect of operating conditions on acylation of 2-methylnaphthalene in a microchannel reactor

被引：2

作者：

Wenpeng Li ^{[1
]}

Suohe Yang ^{[1
]}

Xiaoyan Guo ^{[1
]}

Guangxiang He ^{[1
]}

Haibo Jin ^{[1
]}

机构：

[1] Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology,College of Chemical Engineering,Beijing Institute of Petrochemical Technology

来源：

Chinese Journal of Chemical Engineering | 2018年 / 26卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Acylation; Microchannel reactor; 2-Methylnaphthalene; 2-Methyl-6-propionylnaphthalene;

D O I：

暂无

中图分类号：

O621.25 [];

学科分类号：

070303 ; 081704 ;

摘要：

Acylation of 2-methylnaphthalene(2-MN) is a very important reaction in organic synthesis,and the effiency of the continuous reactor is more than one of the batch reactor.Considering that the Friedel–Crafts acylation is a rapid exothermic reaction,in this study,we perform the acylation of 2-MN in a stainless steel microchannel flow reactor,which is characterized by high mass and heat transfer rates.The effect of reactant ratio,mixing temperature,reaction temperature,and reaction time on product yield and selectivity were investigated.Under the optimal conditions,2-methyl-6-propionylnaphthalene(2,6-MPN) was obtained in 85.8% yield with 87.5% selectivity.Compared with the conventional batch system,the continuous flow microchannel reactor provides a more efficient method for the synthesis of 2,6-MPN.

引用

页码：1307 / 1311

页数：5

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