胰高血糖素样多肽1对2型糖尿病心血管系统的作用

被引:5
作者
桑妙玉 [1 ]
杨小洁 [2 ]
机构
[1] 山西医科大学
[2] 大同市第三人民医院肾病内分泌科
关键词
糖尿病; 胰高血糖素样肽1; 心血管疾病;
D O I
暂无
中图分类号
R587.1 [糖尿病];
学科分类号
1002 ; 100201 ;
摘要
2型糖尿病与心血管疾病风险密切相关。随着胰高血糖素样肽1(GLP-1)及其类似物的广泛应用,其对心血管系统的独特效应成为研究热点。该文概括地介绍和讨论了GLP-1的生理作用,对血糖、血脂、血压和体质量等心血管危险因素的改善作用,分别从抗炎、抗氧化应激、抑制心肌细胞凋亡、减轻缺血/再灌注损伤等角度,探讨GLP-1对血管内皮功能、心力衰竭和缺血性心肌损伤的保护作用。
引用
收藏
页码:1260 / 1262
页数:3
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