A simple and expedient method for the stepwise synthesis of 2-ethoxy-(4H)-3,1-benzoxazine-4-ones

被引：1

作者：

Asrin Bahmani ^{[1
]}

Mahnaz Sharafi-Kolkeshvandi ^{[1
]}

Farzad Nikpour ^{[1
]}

机构：

[1] Department of Chemistry,Faculty of Sciences,University of Kurdistan,P.O.Box 66315-416,Sanandaj,Iran

来源：

ChineseChemicalLetters | 2012年 / 23卷 / 04期

关键词：

2-Ethoxy-(4H)-3; l-benzoxazine-4-ones; Diethyl dicarbonate; Cyanuric chloride; N; N′-Dicyclohexylcarbodiimide; Dehydrocyclization reagent;

D O I：

暂无

中图分类号：

O626 [杂环化合物];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and practical route is described for the synthesis of 2-efhoxy-(4H)-3,1 -benzoxazine-4-ones using the coupling reaction of anthranilic acid derivatives with diethyl dicarbonate following with fast cyclization of the carbamate adduct with a dehydrocyclization agent such as cyanuric chloride and N,N′-dicyclohexylcarbodiimide in PEG at room temperature.High yields of the products obtained under mild reaction conditions with simple work-up of the reaction mixture.

引用

页码：434 / 437

页数：4

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