5-ASA在炎症性肠病相关结直肠癌中的化学预防作用

被引：3

作者：

刘昭诗

钱家鸣

机构：

[1] 中国医学科学院北京协和医学院北京协和医院消化内科

来源：

胃肠病学和肝病学杂志 | 2022年 / 31卷 / 01期

关键词：

5-ASA; 溃疡性结肠炎; 炎症性肠病相关结直肠癌; 化学预防;

D O I：

暂无

中图分类号：

R735.34 [];

学科分类号：

100214 ;

摘要：

癌变是溃疡性结肠炎(ulcerative colitis, UC)最严重的并发症,其预防手段包括内镜监测、分子生物标志物、手术治疗及化学预防。5-氨基水杨酸盐(5-aminosalicylic acid, 5-ASA)是轻-中度UC患者的一线用药,其对炎症性肠病(inflammatory bowel disease, IBD)相关结直肠癌的化学预防作用及机制尚不十分明确。本文较全面地阐述5-ASA的化学预防作用及机制研究进展,旨在为临床实践中预防IBD相关癌变用药方案提供更多依据。

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页码：1 / 4

页数：4

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