miR-221/miR-222与肿瘤

被引:2
|
作者
廖立
奉水东
机构
[1] 南华大学公共卫生学院
关键词
肿瘤; miR-221/mi R-222; 生物标志物;
D O I
暂无
中图分类号
R730.2 [肿瘤病理学、病因学];
学科分类号
摘要
肿瘤的发生是一个多因素参与的阶段性演进过程,研究发现miR-221/mi R-222在多数肿瘤中的表达失调,通过负调控抑癌基因或癌基因的表达,促进或抑制肿瘤的发生、发展。现就miR-221/miR-222在肿瘤中的表达、作用及其临床意义作一综述,并探讨miR-221/miR-222在肿瘤治疗中的潜在价值。
引用
收藏
页码:408 / 411
页数:4
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