Effect of peripheral nerve on the neurite growth from retinal explants in culture

被引:1
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作者
Liu Li and So KwokfaiShanghai Institute of Cell Biology
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retinal explants; peripheral nerve; tissue culture; neurite outgrowth; adult hamster;
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The effect of peripheral nerve (PN)on neurite outgrowth from retinal explants of adult hamsters was examined. Cultures of retinal explants, and co-cultures of retinal explants and PN were performed using chick retinal basement membrane (BM) as substrate. The presence of PN increases the number and length of neurite outgrowth. In addition, a high proportion of neurites situated close to PN tend to grow towards it. Since there was no contact between retinal explants and PN, we suggest that PN might secrete diffusible substances to attract the neurites to grow towards it.
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页码:77 / 87
页数:11
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