共 1 条
[1]
Jeong,J,Tao,B,Sagasser,I,Henniges,H,Sharpless,K.B. J.Am.Chem.Soc . 1998
Extensive Studies on the AlEt3/THF-Promoted Diastereoselec-tive Tandem Rearrangement/Reduction of a-Hydroxy (Amino) Heterocyclopropane: An Efficient Approach to 2-Quaternary 1,3-Diheteroatom Units
被引：0
作者：
李心
王保民
赵学智
高栓虎
涂永强
李得润
机构：
[1] Department of Chemistry & State Key Laboratory of Applied Organic Chemistry
[2] Lanzhou University
[3] Gansu 730000
[4] China
基金：
中国国家自然科学基金;
关键词：
triethyl aluminium;
tandem reaction;
quaternary carbon;
diastereoselectivity;
amino alcohol;
D O I：
暂无
中图分类号：
O621 [有机化学一般性问题];
学科分类号：
070303 ;
081704 ;
摘要：
A facile and highly diastereoselective method for the construction of 2-quaternary 1,3-amino alcohols and 1,3-diols has been developed on the basis of the AlEt3/THF-promoted tandem rearrangement/reductive reaction of a-hydroxy (amino) aziridines (epoxides). The progressive achievement in this article included that both 2-epimers of the units could be constructed from the initially same substrate. Also a stereochemistry assignment we reported previously was corrected.
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页码：1177 / 1182
页数：6
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