新型冠状病毒肺炎合并胸腔积液及心包积液10例临床特征

被引：3

作者：

郭颖韵 ^{[1
]}

张亮 ^{[2
]}

李瑞雪 ^{[3
]}

田山 ^{[1
]}

董卫国 ^{[1
]}

机构：

[1] 武汉大学人民医院消化内科

[2] 武汉大学人民医院放射科

[3] 麻城市人民医院消化内科

来源：

武汉大学学报(医学版) | 2021年 / 42卷 / 06期

关键词：

新型冠状病毒肺炎; 胸腔积液; 心包积液; 临床特征;

D O I：

10.14188/j.1671-8852.2020.0559

中图分类号：

R563.1 [肺炎]; R561.3 [水胸]; R542.12 [];

学科分类号：

摘要：

目的:回顾性分析新型冠状病毒肺炎(COVID-19)合并胸腔积液及心包积液患者的临床特征。方法:收集2020年1月20日至3月23日武汉大学人民医院收治的COVID-19确诊患者的临床资料。分析其中10例合并胸腔积液和心包积液COVID-19患者的特点(积液组),并与50名无胸腔积液且无心包积液的COVID-19患者(对照组)进行对比。采用卡方检验、Fisher确切概率法和Mann-Whitney U进行统计学分析。结果:与对照组相比,积液组患者入院后最高体温(P<0.001)、胸闷症状发生率(P=0.024)、呼吸频率(P=0.004)的差异有统计学意义;生化指标中C-反应蛋白(P=0.039)和D-二聚体(P=0.038)均高于对照组;淋巴细胞(P=0.024)、血红蛋白(P=0.003)、CD4+T细胞(P=0.016)和氧饱和度(P=0.037)均显著低于对照组。积液组的疾病分型重,预后差,差异有统计学意义(P<0.05)。结论:合并胸腔积液和心包积液提示更严重的疾病分型及不良的预后,提示对于合并胸腔积液及心包积液的COVID-19患者应及时给予积极的支持治疗。

引用

页码：878 / 883

页数：6

共 10 条

[1] The Clinical and Chest CT Features Associated With Severe and Critical COVID-19 Pneumonia
Li, Kunhua
Wu, Jiong
Wu, Faqi
Guo, Dajing
Chen, Linli
Fang, Zheng
Li, Chuanming
[J]. INVESTIGATIVE RADIOLOGY, 2020, 55 (06) : 327 - 331
[2] The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China[J] . David S.HuiEsamI AzharTariq A.MadaniFrancineNtoumiRichardKockOsmanDarGiuseppeIppolitoTimothy D.MchughZiad A.MemishabcChristianDrostenabcAlimuddinZumlaEskildPetersenab.International Journal of Infectious Diseases . 2020 (C)
[3] Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia
Wang, Fan
Wang, Haizhou
Fan, Junli
Zhang, Yongxi
Wang, Hongling
Zhao, Qiu
[J]. GASTROENTEROLOGY, 2020, 159 (01) : 367 - 370
[4] Myocardial localization of coronavirus in COVID-19 cardiogenic shock
Tavazzi, Guido
Pellegrini, Carlo
Maurelli, Marco
Belliato, Mirko
Sciutti, Fabio
Bottazzi, Andrea
Sepe, Paola Alessandra
Resasco, Tullia
Camporotondo, Rita
Bruno, Raffaele
Baldanti, Fausto
Paolucci, Stefania
Pelenghi, Stefano
Iotti, Giorgio Antonio
Mojoli, Francesco
Arbustini, Eloisa
[J]. EUROPEAN JOURNAL OF HEART FAILURE, 2020, 22 (05) : 911 - 915
[5] IVIG-mediated effector functions in autoimmune and inflammatory diseases
Galeotti, Caroline
Kaveri, Srini V.
Bayry, Jagadeesh
[J]. INTERNATIONAL IMMUNOLOGY, 2017, 29 (11) : 491 - 498
[6] Clinical Course and Outcomes of Critically Ill Patients With Middle East Respiratory Syndrome Coronavirus Infection
Arabi, Yaseen M.
Arifi, Ahmed A.
Balkhy, Hanan H.
Najm, Hani
Aldawood, Abdulaziz S.
Ghabashi, Alaa
Hawa, Hassan
Alothman, Adel
Khaldi, Abdulaziz
Al Raiy, Basel
[J]. ANNALS OF INTERNAL MEDICINE, 2014, 160 (06) : 389 - +
[7] Influences of pleural effusion on respiratory mechanics, gas exchange, hemodynamics, and recruitment effects in acute respiratory distress syndrome[J] . Chou-Chin Lan,Hsian-He Hsu,Chin-Pyng Wu,Shih-Chun Lee,Chung-Kan Peng,Hung Chang.Journal of Surgical Research . 2014 (1)
[8] Advances in the understanding of the mechanism of action of IVIg[J] . Hartung Hans-Peter.Journal of neurology . 2008 (Supp)
[9] Respiratory syncytial virus infection in patients with hematological diseases: single-center study and review of the literature[J] . Khanna Nina,Widmer Andreas F,Decker Michael,Steffen Ingrid,Halter J?rg,Heim Dominik,Weisser Maja,Gratwohl Alois,Fluckiger Ursula,Hirsch Hans H.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America . 2008 (3)
[10] Clinical characteristics of refractory COVID-19 pneumonia in Wuhan China .2 Mo P,Xing Y,Xiao Y,et al. Clin Infect Dis . 2020

← 1 →