PROTECTIVE EFFECTS OF PENTAGASTRIN AGAINST STRESS-INDUCED GASTRIC LESIONS IN RATS

被引：0
|
作者：
李栋生
戴义隆
陈启盛
肖强
朱启绽
机构：
来源：
中华医学杂志(英文版) | 1986年 / 06期
关键词：
D O I：
暂无
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The rats, pretreated with pentagastrin, 250 μg/kg,daily for 7 days, were given restraint water immersion stress for 3 hours and observed for lesion index of the gastric mucosa. The results showed that the lesion index of the pentagastrin group was significantly decreased as compared with that of the control group. Light and electron microscopically,the mucosal layer was thickened and both the chief cells and parietal cells were in an active state. This suggests that gastrin has protective effects against the stress-induced gastric lesions through its trophic action on the gastrointestinal tract.
引用
收藏
页码：457 / 460
相关论文
共 50 条
  • [21] Role of spasmolytic polypeptide in healing of stress-induced gastric lesions in rats
    Konturek, PC
    Brzozowski, T
    Konturek, SJ
    Elia, G
    Wright, N
    Sliwowski, Z
    Thim, L
    Hahn, EG
    REGULATORY PEPTIDES, 1997, 68 (01) : 71 - 79
  • [22] GASTROPROTECTIVE EFFECT OF NITRENDIPINE ON STRESS-INDUCED GASTRIC-LESIONS IN RATS
    ULAK, G
    CINGI, MI
    EROL, K
    PHARMACOLOGY, 1991, 43 (04) : 220 - 224
  • [23] Role of intracerebroventricular vasopressin in the development of stress-induced gastric lesions in rats
    Büyükcoskun, NI
    Özlük, K
    PHYSIOLOGICAL RESEARCH, 1999, 48 (06) : 451 - 455
  • [24] Protective effects of Weipixiao decoction against MNNG-induced gastric precancerous lesions in rats
    Cai, Tiantian
    Zhang, Chengzhe
    Zeng, Xiaohui
    Zhao, Ziming
    Yan, Yan
    Yu, Xuhua
    Wu, Lei
    Lin, Lin
    Pan, Huafeng
    BIOMEDICINE & PHARMACOTHERAPY, 2019, 120
  • [25] Protective effects of nanocurcumin against stress-induced deterioration in the intestine
    Alinaghipour, Azam
    Salami, Mahmoud
    Riahi, Esmail
    Ashabi, Ghorbangol
    Soheili, Masoud
    Nabavizadeh, Fatemeh
    STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, 2022, 25 (01): : 337 - 346
  • [26] EFFECTS OF OXYTOCIN ON EMOTIONAL-STRESS AND STRESS-INDUCED GASTRIC-LESIONS
    GRASSI, M
    DRAGO, F
    JOURNAL OF PHYSIOLOGY-PARIS, 1993, 87 (04) : 261 - 264
  • [27] THE PROTECTIVE EFFECT OF NUTRIENTS AGAINST STRESS-INDUCED GASTRIC-ULCERS IN THE RAT
    HARJU, E
    SAJANTI, J
    SURGERY GYNECOLOGY & OBSTETRICS, 1987, 165 (06): : 530 - 534
  • [28] The protective of hydrogen on stress-induced gastric ulceration
    Liu, Xinwei
    Chen, Zhi
    Mao, Ningfang
    Xie, Yang
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2012, 13 (02) : 197 - 203
  • [29] Central effect of melatonin against stress-induced gastric ulcers in rats
    Kato, K
    Murai, I
    Asai, S
    Komuro, S
    Matsuno, Y
    Matsukawa, Y
    Kurosaka, H
    Iwasaki, A
    Ishikawa, K
    Arakawa, Y
    NEUROREPORT, 1997, 8 (9-10) : 2305 - 2309
  • [30] Gastroprotective effects of nebivolol and simvastatin against cold restraint stress-induced gastric ulcer in rats
    Kamar, Samaa Samir
    Latif, Noha Samir Abdel
    Elrefai, Mohamed Fathi Mohamed
    Amin, Shaimaa Nasr
    ANATOMY & CELL BIOLOGY, 2020, 53 (03) : 301 - 312
12345