Tumor Cell Apoptosis Inducer from Ganoderma lucidum

被引：0

作者：

ZIMMERMAN-KORDMANN Martin

REUTTER Werner

机构：

[1] InstitutfürMolekularbiologieundBiochemie,FreieUniversittBerlin,Arnimallee,D-Berlin-Dahlem,Germany

来源：

食用菌学报 | 2006年 / 02期

关键词：

Ganoderma lucidum; Apoptosis; Tumor cells;

D O I：

10.16488/j.cnki.1005-9873.2006.02.006

中图分类号：

S567.31 [];

学科分类号：

1008 ;

摘要：

A crude aqueous extract of Ganoderma lucidum fruiting bodies, LZ, inhibited the growth of eight different tumor cell lines in a dose-dependent manner. Two bioactive fractions, LZ-DN-2-2 and LZ-DW-2-a-3, were obtained from LZ using dialysis combined with anion exchange and gel filtration chromatography. LZ, LZ-DN-2-2 and LZ-DW-2-a-3 induced apoptosis of SW620 cells in a dose-dependent manner, and arrested the tumor cells in the G0~ phase of the cell cycle.

引用

页码：23 / 28

页数：6

共 3 条

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[2]

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Anti-allergic constituents in the culture medium of Ganoderma lucidum . (I) Inhibitory effect of oleic acid on histamine release[J] . K. Tasaka,M. Akagi,K. Miyoshi,M. Mio,T. Makino.Agents and Actions . 1988 (3)

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