Objective To observe the clinical efficacy of scalp acupuncture for spastic cerebral palsy(CP),and to explore its possible mechanism based on brain white matter fiber bundles,nerve growth related proteins and inflammatory cytokines.Methods A total of 90 children with spastic CP were randomly divided into a scalp acupuncture group and a sham scalp acupuncture group,45 cases in each group.The children in the two groups were treated with conventional comprehensive rehabilitation treatment.The children in the scalp acupuncture group were treated with scalp acupuncture at the parietal temporal anterior oblique line,parietal temporal posterior oblique line on the affected side,and parietal midline.