Etiology and resistance of asymptomatic bacteriuria isolates among school going children in Sanadaj-Iran

Objective:The objective of this study was to determine the etiology and antimicrobial susceptibility patterns of asymptomatic bacteriuria pathogens isolated among school going children in Sanandaj,Iran.Methods:A total of 1 457 urine samples of 5 to 10 years children from forty different schools of Sanandaj city were screened to see asymptomatic bacteriuria during November 2007 to June 2008.Results:Bacterial colony count of over (105) colony forming units CFU/ mL were found in 28(1.90%) of total cases,with 767(52.64%) girls and 690(47.35%) boys.The highest class-specific prevalence was found in the fourth standard(2.8%) and the lowest in the first standard(1.0%).The dominant bacterial isolates were E.coli 20(74.1%),followed by Klebsiella pneumoniae 04(14.8%) and Staphylococcus aureus 04(14.8%).Cefotaxime,Cefixime,Kanamycin, Co-trimoxazole,nalidicxic acid,nitrofurantoin and Amoxicillin,resistance rates were above 90.0%. Ceftriaxone expressed the highest susceptibility among E.coli isolates.Surprisingly,S.aureus showed 100. 0%resistance to oxacillin.Conclusion:In the present study in which Escherichia coli is the most frequently incriminated as the causative agents.The results show a very serious antibiotic resistance of E.coli isolated. Surveillance and monitoring studies will be essential in preventing of renal scarring or other abnormalities.