SynthesesandAnti-inflammatoryActionof（η-C5H5）2Ti（Cin）2and（η-C5H5）2Ti（Tzea）2

被引：0
作者：
曾正志
机构：
来源：
ChineseJournalofChemistry | 2002年 / 05期
关键词：
cyclopentadienyltitanium; complexes; anti inflammatory;
D O I：
暂无
中图分类号：
O641 [结构化学];
学科分类号：
070304 ; 081704 ;
摘要：
Two new complexes (Cp) 2Ti(Cin) 2 and (Cp) 2Ti(Tzea) 2 (Cp= Cyclopentadienyl η 5 C 5H 5) have been synthesized in THF by the reaction of HCin (Cincofen, 2 phenylquinoline 4 carboxylic acid) or HTzea (5 phenyltetrazolyl 2 ethanoic acid) with (Cp) 2TiCl 2, and characterized by elemental analyses, IR, 1H NMR and 13 C NMR, UV spectra, molar conductivity, TG DTA. In the complexes the carboxyl groups are coordinated to Ti(IV) in a monodentate manner. The inhibitory actions of the complexes on mice ear tumefaction caused by croton oil and the rat foot granulation growth produced by cotton wool are higher than those of the corresponding ligands HCin, HTzea and [(Cp) 2TiCl 2], while their toxicities are lower than those of the free ligands.
引用
收藏
页码：474 / 478
页数：5
相关论文
共 50 条
[41]   Addition of boranes to (E)-(η5-C5H5)2Zr(CH=CHPh)Cl [J].
Ferland, Patrick ;
Prosser, Kathleen E. ;
Bourque, Jeremy L. ;
Edwards, Ian C. ;
Hamilton, Nathan S. ;
Joyce, Lori E. ;
Finniss, Mathew C. ;
Yorke, Scott R. ;
Vogels, Christopher M. ;
Fontaine, Frederic-Georges ;
Decken, Andreas ;
Westcott, Stephen A. .
CENTRAL EUROPEAN JOURNAL OF CHEMISTRY, 2013, 11 (05) :811-816
[42]   Reactivity of [(C5Me5)Fe(C5H4BBr2)] and [(OC)3Mn(C5H4BBr2)] toward Et3SiH: Facile Access to [(OC)3Mn(C5H4BH2)]2 and to Boron-Bridged Dinuclear Organometallics [J].
Eckensberger, U. David ;
Weber, Mitra ;
Wildt, Julia ;
Bolte, Michael ;
Lerner, Hans-Wolfram ;
Wagner, Matthias .
ORGANOMETALLICS, 2010, 29 (21) :5301-5309
[43]   C-H activation of arenes and heteroarenes by early transition metallaborane, [(Cp*Ta)2B5H11] (Cp* = η5-C5Me5) [J].
Bose, Shubhankar Kumar ;
Geetharani, K. ;
Ghosh, Sundargopal .
CHEMICAL COMMUNICATIONS, 2011, 47 (43) :11996-11998
[44]   Diastereotopic groups in two new single-enantiomer structures (R2)P(O)[NH-(+)CH(C2H5)(C6H5)] (R = OC6H5 and C6H5) [J].
Eslami, Farnaz ;
Pourayoubi, Mehrdad ;
Sabbaghi, Fahimeh ;
Skorepova, Eliska ;
Dusek, Michal ;
Baniyaghoob, Sahar .
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2023, 79 :769-+
[45]   Structure of salts of lithium chloride and lithium hexafluorophosphate as solvates with pyridine and vinylpyridine and structural comparisons: (C5H5N)LiPF6, [p-(CH2=CH)C5H4N]LiPF6, [(C5H5N)LiCl]n, and [p-(CH2=CH)C5H4N]2-Li(μ-Cl)2Li[p-(CH2CH)C5H4N]2 [J].
Jalil, AbdelAziz ;
Clymer, Rebecca N. ;
Hamilton, Clifton R. ;
Vaddypally, Shivaiah ;
Gau, Michael R. ;
Zdilla, Michael J. .
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2017, 73 :264-+
[46]   Uranium versus Thorium: Synthesis and Reactivity of [η5-1,2,4-(Me3C)3C5H2]2U[η2-C2Ph2] [J].
Wang, Deqiang ;
Ding, Wanjian ;
Hou, Guohua ;
Zi, Guofu ;
Walter, Marc D. .
CHEMISTRY-A EUROPEAN JOURNAL, 2021, 27 (22) :6767-6782
[47]   Density functional theory study of substituent effects on gas-phase heterolytic Fe-N bond energies of m-G-C 6 H 4 NHFe(CO) 2 ( η 5-C 5 H 5 ) and m-G-C 6 H 4 N(COMe)Fe(CO) 2 ( η 5-C 5 H 5 ) [J].
Zeng, Qing ;
Li, Zucheng ;
Wang, Yi-Bo .
INORGANICA CHIMICA ACTA, 2025, 574
[48]   Molybdenum-Boron Bonds in the Crystal - Structural Characterization of K[η5-C5H5)Mo(CO)3] and [(η5-C5H5) (OC)3Mo-{B(NMe2)-B(NMe2)Br}] [J].
Braunschweig, Holger ;
Radacki, Krzysztof ;
Kraft, Katharina ;
Stellwag, Sascha .
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2010, 65 (09) :1073-1076
[49]   Activation of P4 by U(η5-C5Me5)(η8-C8H6(SiiPr3)2-1,4)(THF); the X-ray structure of [U(η5-C5Me5)(η8-C8H6(SiiPr3)2-1,4)]2(μ-η2:η2-P4) [J].
Frey, Alistair S. P. ;
Cloke, F. Geoffrey N. ;
Hitchcock, Peter B. ;
Green, Jennifer C. .
NEW JOURNAL OF CHEMISTRY, 2011, 35 (10) :2022-2026
[50]   Metathesis reactions of neodymium and dysprosium diiodide-hydrides with organopotassium compounds: structure of [K(THF)2][(5-C5H5)3Nd(-H)Nd(5-C5H5)3] and [K(THF)2][Nd3(PhO)10(THF)4] [J].
Burin, M. E. ;
Logunov, A. A. ;
Fukin, G. K. ;
Bochkarev, M. N. .
JOURNAL OF COORDINATION CHEMISTRY, 2009, 62 (19) :3134-3141
12345