Synthesis and Crystal Structure of tert-Butyl(((2R,3R,6R)-3-hydroxy-6-(nitromethyl)-3,6-dihydro-2H-pyran-2-yl)methyl)carbonate

被引：0

作者：

冯永奎 ^{[1
]}

苏华兰 ^{[1
]}

MUKULA OTUKOL Billy Joel ^{[1
]}

张雪晴 ^{[1
]}

姚辉 ^{[1
]}

黄年玉 ^{[1
]}

机构：

[1] Hubei Key Laboratory of Natural Products Research and Development,Key Laboratory of Functional Yeast (China National Light Industry), College of Biological and Pharmaceutical Sciences, China Three Gorges University

来源：

ChineseJournalofStructuralChemistry | 2021年 / 40卷 / 09期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.14102/j.cnki.0254-5861.2011-3120

中图分类号：

TQ460.1 [基础理论];

学科分类号：

1007 ;

摘要：

In this paper, a β-C-pyranogalactoside(Ⅸ) was synthesized from D-galactose through a nine-step reaction with a total yield of 32% under the palladium catalyst, and its structure was characterized by nuclear magnetic resonance(NMR) and high-resolution electrospray ionization mass spectrometry(HR-ESI-MS). The absolute configuration of this pyranogalactoside was confirmed with a Flack parameter of –0.01(6) by X-ray crystallography using a Cu radiation source. Compound(Ⅸ), CHNO, crystal data: monoclinic system, space group P222, a = 8.53480(10), b = 9.4207(2), c = 18.1308(3) ?, V = 1457.79(4) ?~3, Z = 4, F(000) = 616, Dc =1.318 g/cm3, μ = 0.931 mm, R = 0.0294 and w R = 0.0752 for 2875 independent reflections(R= 0.0163) and 2857 observed ones(I > 2σ(I)).

引用

页码：1205 / 1212

页数：8

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