Expression of an HBV PreS1 Fusion Protein in Escherichia coli

被引:0
作者
金冬雁
曾庆
周园
侯云德
机构
[1] Chinese Academy of Preventive Medicine.Beijing 100052
[2] PRC
[3] State Key Laboratory of Molecular Virologv and Generic Engineering
关键词
hepatitis B virus (HBV) preS1 protein; expression of cloned genes; fusion protein; protein sequencing;
D O I
暂无
中图分类号
Q51 [蛋白质];
学科分类号
071010 ; 081704 ;
摘要
The large protein of the hepatitis B virus (HBV) envelope was subdivided intothe preSl region with 108-115 amino acids, the preS2 region with 55 amino acidsand the S region with 226 amino acids. It was believed that the preSl region cotainedthe hepatocyte attachment sites of the virus as well as multiple highly immunogenicT-cell and B-cell epitopes. The antibody response to the preSl peptide was also oneof the most important serological markers of HBV infection.
引用
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页码:80 / 85
页数:6
相关论文
共 1 条
  • [1] Hou Yunde,Virology and Genetic Engineering: Principles and Methods.Public Health Press. Beijing Review . 1985