细菌群体感应LuxR solos蛋白研究进展

被引:4
作者
叶晓锋 [1 ]
朱军莉 [1 ]
汪海峰 [2 ]
机构
[1] 浙江工商大学食品与生物工程学院浙江省食品安全重点实验室
[2] 浙江农林大学动物科技学院
基金
浙江省自然科学基金;
关键词
LuxR solos蛋白; 群体感应; 细菌交流;
D O I
10.13343/j.cnki.wsxb.20160248
中图分类号
R3411 [];
学科分类号
摘要
N-酰基高丝氨酸内酯(N-acyl-L-homoserine lactones,AHLs)信号分子介导的群体感应(quorum sensing,QS)是一种普遍的革兰氏阴性细菌信息交流方式。AHL-QS系统包括Lux I型AHLs合成酶和LuxR型受体蛋白。然而,部分革兰氏阴性菌缺失1个或多个LuxI型AHLs合成酶,仅有未配对的LuxR型受体蛋白,该LuxR型受体蛋白称为LuxR solo或Orphan蛋白。LuxR solos蛋白在细菌窃听、种间和种内的信号交流中起重要作用,为群体感应研究领域的热点。本文主要综述细菌LuxR solos蛋白的发现、基本概念、蛋白结构及类型,阐述感应AHLs和非AHLs信号分子的重要LuxR solos蛋白及功能,并对群体感应LuxR solos蛋白的研究前景和意义进行了展望。
引用
收藏
页码:341 / 349
页数:9
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