G6PD与肿瘤

被引：3

作者：

王钟 ^{[1
]}

李智宇 ^{[1
]}

李晨媛 ^{[1
]}

孙思 ^{[2
]}

孙圣荣 ^{[1
]}

机构：

[1] 武汉大学人民医院乳腺甲状腺外科

[2] 武汉大学人民医院检验科

来源：

国际肿瘤学杂志 | 2020年 / 47卷 / 12期

关键词：

肿瘤; 磷酸葡糖脱氢酶; 肿瘤形成过程; 生物标志物;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 ;

摘要：

葡萄糖-6-磷酸脱氢酶(G6PD)是磷酸戊糖途径的关键酶, 参与体内多种代谢过程及氧化还原平衡。近年来研究发现, G6PD在多种肿瘤组织中活性升高, 其可调控肿瘤细胞的增殖和凋亡、血管生成、远处转移及放化疗抵抗等, 在肿瘤发生发展中起着重要作用, G6PD有望成为新兴的肿瘤治疗靶点。

引用

页码：728 / 731

页数：4

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