Histone variant H2A.Z facilitates DNA replication

被引：0
|
作者：
Lei Qiu [1 ]
Xinyi Zeng [1 ]
Junhong Han [1 ]
机构：
[1] Department of Abdominal Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy
来源：
Science China(Life Sciences) | 2020年 / 05期
基金：
中国国家自然科学基金;
关键词：
origin; DNA; Histone variant H2A.Z facilitates DNA replication;
D O I：
暂无
中图分类号：
Q75 [分子遗传学];
学科分类号：
071007 ;
摘要：
In eukaryotes, DNA wraps around the histone octamer to form nucleosomes, which are further compacted into the chromosome structure. The chromosome contains multiple replication origins that are regulated by both DNA sequence and epigenetic features. DNA replication begins in G1 phase with the assembly of pre-replication complexes, including
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收藏
页码：788 / 790
页数：3
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