Design,synthesis,in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antibacterial,antifungal and anti-tubercular agents

被引：7

作者：

Tarunkumar Nanjibhai Akhaja

Jignesh Priyakant Raval

机构：

[1] DepartmentofPharmaceuticalChemistry,Ashok&RitaPatelInstituteofIntegratedStudyandResearchinBiotechnologyandAlliedSciences(ARIBAS),NewVallabhVidyanagar-,Gujarat,India

来源：

ChineseChemicalLetters | 2012年 / 23卷 / 04期

关键词：

Tetrahydropyrimidines; Isatin; 1,3-Dihydro-2H-indol-2-ones; Biginelli reaction; CaCl2; catalyst; In vitro antituberculer activity; Antibacterial and antifungal activity;

D O I：

暂无

中图分类号：

TQ465 [抗菌素制造];

学科分类号：

100705 ;

摘要：

A series of 5-substitued-3-(5-(4-(furan-2-yl)-6-methyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-thiadiazol-2- ylimino)indolin-2-one derivatives were synthesized,characterized and were screened for anti-bacterial,anti-fungal and antitubercular activity.

引用

页码：446 / 449

页数：4