Liver involvement in pediatric celiac disease

被引：0

作者：

Caterina Anania ^{[1
]}

Ester De Luca ^{[1
]}

Giovanna De Castro ^{[1
]}

Claudio Chiesa ^{[2
]}

Lucia Pacifico ^{[1
]}

机构：

[1] Department of Pediatrics and Child Neuropsychiatry,Sapienza University of Rome, Rome, Viale Regina Elena

[2] Institute of Translational Pharmacology,National Research Council, Via Fosso del Cavaliere

来源：

World Journal of Gastroenterology | 2015年 / 19期

关键词：

Celiac disease; Cryptogenic hypertransaminasemia; Autoimmune liver disease; End-stage liver disease; Fatty liver;

D O I：

暂无

中图分类号：

R725.7 [小儿消化系及腹部疾病];

学科分类号：

100202 ;

摘要：

Celiac disease(CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America. Although the disease primarily affects the gut,the clinical spectrum of CD is remarkably varied, andthe disease can affect many extraintestinal organs and systems, including the liver. The hepatic dysfunction presenting in CD ranges from asymptomatic liver enzyme elevations or nonspecific reactive hepatitis(cryptogenic liver disorders), to chronic liver disease.In this article, we review the clinical presentations and possible mechanisms of CD-related liver injury to identify strategies for the diagnosis and treatment of these disorders in childhood.

引用

页码：5813 / 5822

页数：10

共 45 条

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