Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata

被引：1

作者：

Chuangfeng Zhang ^{[1
]}

Jian Zhou ^{[1
,2
]}

Jingzhi Yang ^{[1
]}

Chuangjun Li ^{[1
]}

Jie Ma ^{[1
]}

Dan Zhang ^{[1
]}

Dongming Zhang ^{[1
]}

机构：

[1] State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College

[2] Department of Pharmacy, The First Affiliated Hospital of Nanchang University

来源：

ActaPharmaceuticaSinicaB | 2016年 / 6卷 / 06期

关键词：

Lespedeza cuneata; Phenylpropanoid glycosides; Extraction and isolation; Hepatoprotective activity; Cuneataside E; Cuneataside F;

D O I：

暂无

中图分类号：

R284 [中药化学];

学科分类号：

1008 ;

摘要：

Two new phenylpropanoid glycosides named cuneataside E(1) and cuneataside F(2), were isolated from the aerial parts of Lespedeza cuneata(Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis(UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1showed moderate hepatoprotective activity against N-acetyl-p-aminophenol(APAP)-induced toxicity in He G2 cells.

引用

页码：564 / 567

页数：4

共 3 条

[1]

Phenylpropanoid and lignan glycosides from the aerial parts of Lespedeza cuneata[J] . Jian Zhou,Chuang-Jun Li,Jing-Zhi Yang,Jie Ma,Lian-Qiu Wu,Wen-Jie Wang,Dong-Ming Zhang. Phytochemistry . 2016

[2]

Flavonoids from the aerial parts of Lespedeza cuneata[J] . Dong-Joo Kwon,Young-Soo Bae. Biochemical Systematics and Ecology . 2008 (1)

[3] New flavonoids and other constituents from Lespedeza cuneata [J].

Deng, Fei ;

Chang, Jun ;

Zhang, Jin-Sheng .

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2007, 9 (07) :655-658

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