Communication and monitor of breast cancer signal in the pulse-output genetic circuit network

被引：0

作者：

WANG Xiang ^{[1
]}

YUAN GuangQian ^{[1
]}

WANG Xun ^{[1
]}

ZHAO ZeXi ^{[1
]}

WANG Kan ^{[2
]}

机构：

[1] School of Electronic and Information Engineering,Beihang University

[2] Carleton College

来源：

Science China(Information Sciences) | 2014年 / 57卷 / 03期

基金：

中国国家自然科学基金;

关键词：

genetic circuit network; pulse; multi-index; breast cancer signal; communication;

D O I：

暂无

中图分类号：

R737.9 [乳腺肿瘤]; TN873 [显示设备、显示器];

学科分类号：

0810 ; 081001 ; 100214 ;

摘要：

Pulse-output genetic circuit networks have the advantages in stability and accuracy.In this paper,we analyze some important parameters in a typical inverter,and then design a pulse-output genetic circuit of breast cancer signal communication and monitor of breast cancer signal.We first design a single-index monitor circuit.When a certain tumor marker’s concentration exceeds the positive criterion,the circuit will output a pulse as a warning.Since the diagnose results derived from one single tumor marker are sometimes indeterminate,an integrated circuit is proposed to construct a multi-index monitor circuit network.The multi-index detection can strongly increase the correct recognition rate in terms of accuracy and safety.This circuit network may also be used in other fields of gene diagnosis with some modifications,and some experiments designed to validate them had been done.

引用

页码：66 / 75

页数：10