Application of nanodiamonds in human body fluid analysis by matrix-assisted laser desorption/ionization mass spectrometry

被引:0
作者
孔祥蕾
机构
[1] InstituteofAtomicandMolecularSciences,AcademiaSinica
关键词
MS; MALDI; Application of nanodiamonds in human body fluid analysis by matrix-assisted laser desorption/ionization mass spectrometry; body; HCCA;
D O I
暂无
中图分类号
R446.1 [生物化学检验、临床检验];
学科分类号
100208 ;
摘要
<正>Direct mass spectrometric analysis of complex biological samples is very important and challenging.In this paper,nanodiamonds have been successfully used in matrix-assisted laser desorption/ionization mass spectrometric analysis of human serum and urine.As a practical tool and platform,it can be widely used in the field of humoral proteomics,and it plays a very promising role in clinical diagnosis,including identification of novel disease-associated biomarkers.
引用
收藏
页码:417 / 420
页数:4
相关论文
共 23 条
[1]  
T.W.Hutchens,and T.-T.Yip. Rapid Commun.Mass Speetrom . 1993
[2]  
N.Tang,P.Tornatore,and S.R.Weinberger. Mass Spec- trom.Rev . 2004
[3]  
L.-C.L.Huang,and H.-C.Chang. Langmuir . 2004
[4]  
X.L.Kong,L.C.L.Huang,C.-M.Hsu,W.-H.Chen,C.- C.Han,and H.-C.Chang. Analytical Chemistry . 2005
[5]  
J.M.Koomen,L.N.Shih,K.R.Coombes,D.Li,L.-C. Xiao,I.J.Fidler,J.L.Abbruzzese,and R.Kobayashi. Chin.Cancer Res . 2005
[6]  
M.Karas,and F.Hillenkamp. Analytical Chemistry . 1988
[7]  
K.Tanaka,H.Waki,Y.Ido,S.Akita,and Y.Yoshida. Rapid Commun.Mass Spectrum . 1988
[8]  
Principles and Practices of Biological Mass Spectrometry. C.Dass. . 2001
[9]  
L.Zhou,X.Gu,Y.Zhu,X.Guo,W.Zhao,H.Zheng,L. Fang,and W.Zhang. Chinese Journal of Lasers . 2006
[10]  
G.L.Hortin. Clin.Chem . 2006