Recent advances of sonodynamic therapy in cancer treatment

被引:1
作者
GuoYun Wan [1 ]
Yang Liu [1 ,2 ]
BoWei Chen [1 ]
YuanYuan Liu [1 ]
YinSong Wang [1 ]
Ning Zhang [1 ,2 ]
机构
[1] Research Center of Basic Medical Science & School of Pharmacy, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), Tianjin Medical University
[2] Laboratory of Cancer Cell Biology, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital
关键词
Sonodynamic therapy; sonosensitizer; cancer; ultrasound; reactive oxygen species;
D O I
暂无
中图分类号
R730.5 [肿瘤治疗学];
学科分类号
100214 ;
摘要
Sonodynamic therapy(SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid tumors in a site-directed manner.In this article, we critically reviewed the currently accepted mechanisms of sonodynamic action and summarized the classification of sonosensitizers. At the same time, the breath of evidence from SDT-based studies suggests that SDT is promising for cancer treatment.
引用
收藏
页码:325 / 338
页数:14
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