Regulation of scleral fibroblast differentiation by bone morphogenetic protein-2

被引：0
|
作者：
Hong-Hui Li [1 ]
Li-Jun Huo [1 ]
Zhen-Ya Gao [1 ]
Feng Zhao [1 ]
Jun-Wen Zeng [1 ]
机构：
[1] State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-Sen University
来源：
International Journal of Ophthalmology | 2014年 / 01期
基金：
中国国家自然科学基金;
关键词：
bonemorphogeneticprotein-2; sclera; myopia;
D O I：
暂无
中图分类号：
R329.2 [人体细胞学];
学科分类号：
100101 ;
摘要：
Bone morphogenesis proteins(BMPs) are multi-functional growth factors. They are expressed in retina,retinal pigment epithelium(RPE) and sclera and serve as a regulator in the growth and development of the eye. This article reviewed the chondrogenic potency of the sclera,biochemical and pathological changes of myopic scleral tissue and the differentiation of chondrogenesis by BMP-2. We proposed the hypothesis that BMP-2 can regulate differentiate of scleral fibroblasts and affect the development of myopia.
引用
收藏
页码：152 / 156
页数：5
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