<正> A high-speed high-sensitivity swept source optical coherence tomography (SSOCT) system using a highspeed swept laser source is developed.Non-uniform discrete fourier transform (NDFT) method is introducedin the SSOCT system for data processing.Frequency calibration method based on a Mach-Zenderinterferometer (MZI) and conventional data interpolation method is also adopted in the system for cornparison.Optical coherence tomography (OCT) images from SSOCT based on the NDFT method,the MZImethod,and the interpolation method are illustrated.The axial resolution of the SSOCT based on theNDFT method is comparable to that of the SSOCT system using MZI calibration method and conventionaldata interpolation method.The SSOCT system based on the NDFT method can achieve higher signalintensity than that of the system based on the MZI calibration method and conventional data interpolationmethod because of the better utilization of the power of source.