Helicobacter pylori infection and atopic diseases:Is there a relationship? A systematic review and meta-analysis

被引：2

作者：

Elena Lionetti ^{[1
]}

Salvatore Leonardi ^{[1
]}

Angela Lanzafame ^{[1
]}

Maria Teresa Garozzo ^{[1
]}

Martina Filippelli ^{[1
]}

Stefania Tomarchio ^{[1
]}

Viviana Ferrara ^{[1
]}

Carmelo Salpietro ^{[2
]}

Alfredo Pulvirenti ^{[3
]}

Ruggiero Francavilla ^{[4
]}

Carlo Catassi ^{[5
]}

机构：

[1] Department of Pediatrics,University of Catania,95100 Catania,Italy

[2] Department of Pediatrics,Unit of Pediatric Genetics and Immunology,University of Messina,98125 Messina,Italy

[3] Department of Clinical and Molecular Biomedicine,University of Catania,95100 Catania,Italy

[4] Department of Developmental Medicine,University of Bari,70124 Bari,Italy

[5] Department of Pediatrics,Università Politecnica delle Marche,60123 Ancona,Italy

来源：

World Journal of Gastroenterology | 2014年 / 46期

关键词：

Atopy; Allergic diseases; Helicobacter pylori; Hygiene hypothesis; Infection;

D O I：

暂无

中图分类号：

R573 [胃疾病];

学科分类号：

1002 ; 100201 ;

摘要：

AIM:To review and conduct a meta-analysis of the existing literature on the relationship between Helicobacter pylori(H.pylori),atopy and allergic diseases.METHODS:Studies published in English assessing the prevalence of atopy and/or allergic diseases in patients with H.pylori infection and the prevalence of H.pylori infection in patients with atopy and/or allergic diseases were identified through a MEDLINE search(1950-2014).Random-effect model was used for the meta-analysis.RESULTS:Pooled results of case-control studies showed a significant inverse association of H.pylori infection with atopy/allergic disease or with exclusively atopy,but not with allergic disease,whereas pooled results of cross-sectional studies showed only a significant association between allergic disease and H.pylori infection.CONCLUSION:There is some evidence of an inverse association between atopy/allergic diseases and H.pylori infection,although further studied are needed.

引用

页码：17635 / 17647

页数：13

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