ZIKV viral proteins and their roles in virus-host interactions

被引:0
|
作者
Moujian Guo [1 ]
Lixia Hui [1 ]
Yiwen Nie [1 ]
Boris Tefsen [2 ]
Ying Wu [1 ,3 ]
机构
[1] State Key Laboratory of Virology,School of Basic Medical Sciences,Wuhan University
[2] Department of Biological Sciences,Xi'an Jiaotong-Liverpool University
[3] Hubei Province Key Laboratory of Allergy and Immunology
关键词
ZIKV; viral protein; host-virus interactions; immune response; pathogenicity;
D O I
暂无
中图分类号
R373 [人体病毒学(致病病毒)];
学科分类号
100103 ; 100705 ;
摘要
The re-emergence of Zika virus(ZIKV) and its associated neonatal microcephaly and Guillain-Barré syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKVin the process of ZIKVinfection and pathogenicity. These studies have provided significant insights for the treatment and prevention of ZIKV infection. Here we review the current research advances in the functional characterization of the interactions between each ZIKV viral protein and its host factors.
引用
收藏
页码:709 / 719
页数:11
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