The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus

被引:0
作者
Consortium for Influenza Study at Shanghai(HE YunGang1
Center of Bioinformatics
Lab of Synthetic Biology
Institute Pasteur)
2 School of Life Sciences
3 Shanghai-MOST Key Laboratory for Disease and Health Genomics
4 Cancer Institute
5 School of Life Sciences and Technology
6 National Engineering Research Center for Antibody Drugs
7 Zhujiang Hospital
8 Shanghai Municipal Center for Disease Control & Prevention
9 Shanghai Center for Bioinformation Technology
10 School of Life Sciences and Technology
11 National Institute for Parasitic Diseases
12 Shanghai Institute of Organic Chemistry
13 Shanghai Veterinary Research Institute
14 National Engineering Research Center for Biochip Technology
机构
关键词
influenza; novel type A(H1N1) virus; hemagglutinin; gene mutation;
D O I
暂无
中图分类号
R511.7 [流行性感冒]; R181.3 [流行病学各论];
学科分类号
100401 ;
摘要
A mutation network for the hemagglutinin gene(HA) of the novel type A(H1N1) influenza virus was constructed.Sequence homology analysis indicated that one HA sequence type from the viruses mainly isolated from Mexico was likely the original type in this epidemic.Based on the 658A and 1408T mutations in HA,the viruses evolving into this epidemic were divided into three categories,the Mexico,the transitional and the New York type.The three groups of viruses presented distinctive clustering features in their geographic distributions.
引用
收藏
页码:2168 / 2170
页数:3
相关论文
共 1 条
  • [1] The influenza virus resource at the National Center for Biotechnology Information .2 Bao Y,Bolotov P,Dernovoy D,et al. J Virol . 2008